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[2] Q. Wang^#, C. C. Zeng^#, Z. Q. Chen, L. Hu, J. X. Dou, C. K. Ye, L. B. Zhu, Q. R. Liang, H. M. Pan, W. Jiang*, Y. C. Wang*. Nanoparticles reach metastatic tumours via enhanced permeability of adjacent vessels. Nature Nanotechnology. 2026;21(6):880-891.

[3] H. Zhou^#, Q. R. Liang^#, Y. C. Wang*. Living therapeutic depots: Matching design to therapeutic needs. Cell Stem Cell. 2026;33(8):1254-1256.

[4] B. W. Zhang^#, Y. Y. Wang^#, D. Chen, M. Y. Li, J. C. Zhang, Y. Wu, J. X. Xia, X. Y. Meng, Y. C. Wang*, M. Li*. Engineering a dual-antigen mRNA vaccine to restore immune control in chronic hepatitis B. Nature Communication. 2026;17(1):7686.

[5] Q. Wang^#, S. S. Chen^#, G. Li^#, T. L. Hou, T. Y. Yao, M. Zhou, Z. Liu*, W. Jiang*, Y. C. Wang*. Engineering Polymer–Lipid Integrated Nanoparticles with Quantitative Design Principles for Organ-Selective mRNA Delivery. Journal of the American Chemical Society. 2026;148(12):13079-13091.

[6] H. Liu, Z. Q. Chen, Y. N. Fan*, Y. C. Wang*. The next phase of nanocarrier-enabled in vivo CAR-T therapy. Nano Today. 2026 Aug 30;72:103155.

[7] Q. R. Liang, H. Zhou, Y. C. Wang*. Host biology as a determinant of in vivo delivery and its translational potential. Clinical and Translational Medicine. 2026;16(8):e70791.

[1] W. Jiang#, Z. X. Guo#, Q. Wang#,*, Z. Q. Chen, W. Dong, Q. R. Liang, Y. H. Hao, H. M. Pan, C. C. Zeng, H. Liu*, Y. C. Wang*. Enhanced nanoparticle delivery across vascular basement membranes of tumours using nitric oxide. Nature Biomedical Engineering. 2025, 9(9):1486-1501.

[2] Y. Liu#, Q. Liu#, B. W. Zhang#, S. S. Chen, Y. Q. Shen, Z. B. Li, J. C. Zhang, Y. Yang, M. Li*, Y. C. Wang*. Generation of tolerogenic antigen-presenting cells in vivo via the delivery of mRNA encoding PDL1 within lipid nanoparticles. Nature Biomedical Engineering. 2025, 9(8):1320-1334.

[3] Z. Q. Shen#, W. Jiang#, S. Q. Zheng, S. Y. Luo, Z. X. Guo, Q. Wang, Y. C. Wang*, J. M. Hu*. Intracellular co-delivery of carbon monoxide and nitric oxide induces mitochondrial apoptosis for cancer therapy. Angewandte Chemie International Edition. 2025, 64(7):e202419939.

[4] W. X. Deng#, Y. Y. Wang#, J. Y. Wang, Y. T. Su, M. Y. Li, K. Qu, Y. C. Wang*, M. Li*. Leveraging vitamin C to augment nanoenabled photothermal immunotherapy. ACS Nano. 2025, 19(13):12982-12995.

[5] T. Ji, P. Ge, S. Zhang, C. J. Wan, H. L. Liu, X. Z. Qu, F. Zhu, Q. G. Gong, W. Y. Xu, C. Wang*, Y. C. Wang*, C. D. Huang*. Remote on–off switching of protein activity by intrinsically disordered region. Nature Structural & Molecular Biology. 2025, 32(10):2088-2098.

[1] Q. Wang^#, Q. R. Liang^#, J. X. Dou, H. Zhou, C. C. Zeng, H. M. Pan, Y. Q. Shen, Q. Li, Y. Liu, D. T. Leong*, W. Jiang*, Y. C. Wang*. Breaking through the basement membrane barrier to improve nanotherapeutic delivery to tumours. Nature Nanotechnology. 2024, 19(1):95-105.

[2] M. Luo^#, Q. Wang^#, G. Zhao^#, W. Jiang, C. C. Zeng, Q. A. Zhang, R. Y. Yang, W. Dong, Y. X. Zhao, G. Z. Zhang, J. Jiang, Y. C. Wang*, Q. Zhu*. Solid-state atomic hydrogen as a broad-spectrum RONS scavenger for accelerated diabetic wound healing. National Science Review. 2024, 11(2):nwad269.

[3] H. Zhou^#, Y. Wu^#, M. Li^#, Q. R. Liang, W. Dong, Q. Li*, Y. C. Wang*. Modular satellite nanoparticles for remedying primary and secondary injury in cerebral ischemia-reperfusion. Advanced Functional Materials. 2024, 34(30):2315274.

[4] W. Dong^#, Z. B. Li^#, T. L. Hou^#, Y. Q. Shen, Z. X. Guo, Y. T. Su, Z. Q. Chen, H. M. Pan, W. Jiang*, Y. C. Wang*. Multicomponent synthesis of imidazole-based ionizable lipids for highly efficient and spleen-selective messenger RNA delivery. Journal of the American Chemical Society. 2024, 146(22):15085-15095.

[5] M. Hassan^#, Y. T. Su^#, S. Z. Iqbal, R. Nawaz, Y. C. Wang*, W. Jiang*. Symmetrically fluorinated D-π-A structured cyanine dye for highly efficient NIR-II imaging-guided cancer phototheranostics. Small. 2024, 20(43):2401905.

[6] Q. Liu^#, L. Wang^#, Y. T. Su, W. Dong, H. R. Wang, Y. Liu, H. Liu*, L. X. Liu*, Y. C. Wang*. Ultrahigh enzyme loading metal-organic frameworks for deep tissue pancreatic cancer photoimmunotherapy. Small. 2024, 20(10): 2305131.

[7] N. M. Wu^#, J. C. Zhang^#, Y. Q. Shen^#, X. H. Zhang^#, J. G. Zhou^#, Y. Wu, E. T. Li, X. M. Meng, X. Chuai*, S. Chiu*, Y. C. Wang*. A potential bivalent mRNA vaccine candidate protects against both RSV and SARS-CoV-2 infections. Molecular Therapy. 2024, 32(4):1033-1047.

[8] Z. X. Guo^#, C. C. Zeng^#, Y. Q. Shen^#, L. Hu, H. Y. Zhang, Z. B. Li, W. Dong, Q. Wang, Q. Liu, Y. C. Wang*, W. Jiang*. Helper lipid-enhanced mRNA delivery for treating metabolic dysfunction-associated fatty liver disease. Nano Letters. 2024, 24(22):6743-6752.

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[10] 李港, 侯泰霖, 蒋为, 王育才*. 聚合物载体在 mRNA 递送领域的研究进展. 药学进展. 2024, 48(6):437-449.

[1] X. Cheng^#, T. Xu^#, W. Y. You, T. Wang, D. M. Zhang, H. M. Guo, H. Y. Zhang, X. Pan, Y. C. Wang, L. Liu, K. G. Zhang, J. Shi, X. B. Yao, J. Guo*, Z. Y. Yang*. A mitotic NADPH upsurge promotes chromosome segregation and tumour progression in aneuploid cancer cells. Nature Metabolism. 2023, 5(7): 1141-1158.

[2] M. Li^#, H. Zhou^#, M. H. Fang, K. Qu, Y. C. Wang*. Cationic lipids-mediated dual-targeting of both dendritic cells and tumor cells for potent cancer immunotherapy. Advanced Functional Materials. 2023, 33(46): 2306752.

[3] M. I. Setyawati^#*, Q. Wang^#, N. Y. Ni, J. K. Tee, K. Ariga, P. C. Ke, H. K. Ho, Y. C. Wang*, D. T. Leong*. Engineering tumoral vascular leakiness with gold nanoparticles. Nature Communications. 2023, 14(1): 4269.

[4] K. G. Chen^#, Z. Zhang^#, Z. Y. Fang^#, J. C. Zhang, Q. Liu, W. Dong, Y. Liu, Y. C. Wang*, J. Wang*. Aged-signal-eliciting nanoparticles stimulated macrophage-mediated programmed removal of inflammatory neutrophils. ACS Nano. 2023, 17(14): 13903-13916.

[5] Y. Wu^#, N. M. Wu^#, X. Y. Jia^#, Y. Wu^#, X. H. Zhang, Y. Liu, Y. X. Hou, Y. Q. Shen, E. T. Li, W. Wang*, Y. C. Wang*, S. Chiu*. Long-term immune response to Omicron-specific mRNA vaccination in mice, hamsters, and nonhuman primates. MedComm. 2023, 4(6): e460.

[6] Liu^#, W. Dong^#, Y. C. Ma, J. X. Dou, W. Jiang, L. Wang, Q. Wang, S. Y. Li, Y. C. Wang*, M. Li*. Nanomedicines with high drug availability and drug sensitivity overcome hypoxia-associated drug resistance. Biomaterials. 2023, 294: 122023.

[7] K. G. Chen^#, Z. Zhang^#, J. C. Zhang^#, Z. Y. Fang, W. Dong, Y. C. Wang*, M. Li*. Antigen-caged-adjuvant nanovaccines elicit potent humoral and cellular immune responses. Nano Today. 2023, 53: 102036.

[8] W. Jiang^#, Z. Shen^#, Z. Guo^#, Q. Wang, Q. Li, J. Hu*, Y. C. Wang*. Overcoming oxygen heterogeneity of tumor microenvironments to boost cancer immunotherapy by oxygen-switchable ROS/RNS nanogenerators. Nano Today. 2023, 48: 101696.

[9] Y. C. Xu^#, C. Yang^#, Y. Wu, W. Jiang, Q. Cheng, L. F. Yan, K. G. Chen*, Y. C. Wang*. In situ albumin-hitchhiking NIR-II probes for accurate detection of micrometastases. Nano Letters. 2023, 23(12): 5731-5737.

[10] M. Li^#, H. Zhou^#, N. M. Wu, W. X. Deng, W. Dong, X. Sun, H. Liu, Z. G. Tian, Y. C. Wang*. Pathogen recognition-driven dendritic cell-specific gene silencing and editing. Nano Letters. 2023, 23(7): 2733-2742.

[11] W. X. Duan, L. F. Hang, Y. C. Ma, Q. Wang, X. F. Tang, W. Jiang, Y. Wu, W. F. Lv, Y. C. Wang*. Compartmentalized nano-MOFs as co-delivery systems for enhanced antitumor therapy. ACS Applied Materials & Interfaces. 2023, 15(33): 39039-39052.

[1] Y. Wu^#, Y. Q. Shen^#, N. M. Wu^#, X. H. Zhang^#, S. H. Chen, C. Yang, J. H. Zhou, Y. Wu, D. Chen, L. Wang, C. Wang, H. J. Zhang*, N. N. Xia*, S. Chiu*, Y. C. Wang*. Omicron-specific mRNA vaccine elicits potent immune responses in mice, hamsters, and nonhuman primates. Cell Research. 2022, 32(10): 949-952.

[2] G. R. Zhang^#, Q. Wang^#, W. Y. Tao^#, W. Jiang, E. Elinav, Y. C. Wang*, S. Zhu*. Glucosylated nanoparticles for the oral delivery of antibiotics to the proximal small intestine protect mice from gut dysbiosis. Nature Biomedical Engineering. 2022, 6(7): 867-881.

[3] Q. Zhu^#, W. Jiang^#, K. Ye, S. R. Jin, W. Dong, S. D. Liu, G. Z. Zhang, C. Tian, Y. Luo, Y. C. Wang*, J. Jiang*. Hydrogenated oxide material for self-targeting and automatic-degrading photothermal tumor therapy in the NIR-II bio-window. Advanced Functional Materials. 2022, 32(14): 2110881.

[4] W. Jiang^#, W. Dong^#, M. Li^#, Z. X. Guo, Q. Wang, Y. Liu, Y. H. Bi, H. Zhou, Y. C. Wang*. Nitric oxide induces immunogenic cell death and potentiates cancer immunotherapy. ACS Nano. 2022, 16(3): 3881-3894.

[5] Y. H. Zhu^#, X. F. Tang^#, Q. Liu^#, Y. J. Xia, X. W. Zhai, H. Zhang, D. L. Duan, H. Wang, W. Q. Zhan, L. Wu, N. Zheng, W. F. Lv*, Y. C. Wang*, M. Zhou*. Metallic carbonitride MXene based photonic hyperthermia for tumor therapy. Small. 2022, 18(22): 2200646.

[6] L. Wang^#, J. X. Dou^#, W. Jiang, Q. Wang, Y. Liu, H. Liu*, Y. C. Wang*. Enhanced intracellular transcytosis of nanoparticles by degrading extracellular matrix for deep tissue radiotherapy of pancreatic adenocarcinoma. Nano Letters. 2022, 22(17): 6877-6887.

[1] M. J. Cao^#, R. Cai^#, L. N. Zhao^#, M. Y. Guo^#, L. M. Wang, Y. C. Wang, L. L. Zhang, X. F. Wang, H. D. Yao, C. Y. Xie, Y. L. Cong, Y. Guan, X. Y. Tao, Y. L. Wan, S. X. Xu, Y. Liu, Y. L. Zhao, C. Y. Chen*. Molybdenum derived from nanomaterials incorporates into molybdenum enzymes and affects their activities in vivo. Nature Nanotechnology. 2021, 16(6):708-716.

[2] Y. H. Bi^#, W. X. Duan^#, J. Chen^#, T. You*, S. Y. Li, W. Jiang, M. Li, G. Wang, X. Y. Pan, J. Wu, D. Liu, J. Li*, Y. C. Wang*. Neutrophil decoys with anti-inflammatory and anti-oxidative properties reduce secondary spinal cord injury and improve neurological functional recovery. Advanced Functional Materials. 2021, 31(34):2102912.

[3] W. Jiang^#, L. Wang^#, Q. Wang, H. Zhou, Y. C. Ma, W. Dong, H. X. Xu*, Y. C. Wang*. Reversing immunosuppression in hypoxic and immune cold tumors with ultrathin oxygen self-supplementing polymer nanosheets under near infrared light irradiation. Advanced Functional Materials. 2021, 31(3):2100354.

[4] Y. Wu^#, W. Jiang^#, S. H. Huo^#, S. Y. Li, Y. C. Xu, S. G. Ding, J. Zhou, H. Liu*, W. F. Lv*, Y. C. Wang*. Nano-metal-organic-frameworks for treating H₂O₂-secreting bacteria alleviate pulmonary injury and prevent systemic sepsis. Biomaterials. 2021, 279:121237.

[5] M. Li^#, D. Xie^#, X. F. Tang^#, C. Yang, Y. Q. Shen, H. Zhou, W. X. Deng, J. W. Liu, S. B. Cai, L. Bai*, Y. C. Wang*. Phototherapy facilitates tumor recruitment and activation of natural killer T cells for potent cancer immunotherapy. Nano Letters. 2021, 21(14):6304-6313.

[6] W. Jiang^#, H. Zhou^#, Q. Wang^#, Z. Chen, W. Dong, Z. Guo, Y. Li, W. Zhao, M. Zhan*, Y. C. Wang*, L. Lu*. High drug loading and pH-responsive nanomedicines driven by dynamic boronate covalent chemistry for potent cancer immunotherapy. Nano Research. 2021, 14(11):3913-3920.

[1] S. Li^#, M. Li^#, S. Huo, Q. Wang, J. Chen, S. Ding, Z. Zeng, W. Zhou, Y. C. Wang*, J. Wang*. Voluntary opsonization-enabled precision nanomedicines for inflammation treatment. Advanced Materials. 2020, 33(3):2006160.

[2] L. Wang^#, W. Jiang^#, L. Xiao^#, H. J. Li, Z. Q. Chen, Y. Liu, J. X. Dou, S. Y. Li, Q. Wang, W. Han, Y. C. Wang*, H. Liu*. Self-reporting and splitting nanopomegranates potentiate deep tissue cancer radiotherapy via elevated diffusion. ACS Nano. 2020, 14(7):8459-8472.

[3] M. Li^#, S. Li^#, H. Zhou, X. Tang, Y. Wu, W. Jiang, Z. Tian, X. Zhou, X. Yang, Y. C. Wang*. Chemotaxis-driven delivery of nano-pathogenoids for complete eradication of tumors postphototherapy. Nature Communications. 2020, 11(1):1126.

[4] M. Li^#, H. Zhou^#, W. Jiang^#, C. Yang, H. Miao, Y. C. Wang*. Nanovaccines integrating endogenous antigens and pathogenic adjuvants elicit potent antitumor immunity. Nano Today. 2020, 35:101007.

[5] Q. Li^#, L. Hang^#, W. Jiang^#, J. Dou, L. Xiao, X. Tang, Y. Yao*, Y. C. Wang*. Pre- and post-irradiation mild hyperthermia enabled by NIR-II for sensitizing radiotherapy. Biomaterials. 2020, 257:120235.

[6] S. Li, Q. Wang, Y. Shen, M. Hassan, J. Shen, W. Jiang, Y. Su, J. Chen, L. Bai, W. C. Zhou, Y. C. Wang*. Pseudoneutrophil cytokine sponges disrupt myeloid expansion and tumor trafficking to improve cancer immunotherapy. Nano Letters. 2020, 20(1):242-251.

[7] M. Li, H. Zhou, C. Yang, Y. Wu, X. Zhou, H. Liu*, Y. C. Wang*. Bacterial outer membrane vesicles as a platform for biomedical applications: an update. Journal of Controlled Release. 2020, 323:253-268.

[8] L. Wang^#, S. Li^#, W. Jiang, H. Liu, J. Dou, X. Li*, Y. C. Wang*. Polyphosphoestered nanomedicines with tunable surface hydrophilicity for cancer drug delivery. ACS Applied Materials & Interfaces. 2020, 12(29):32312-32320.

[1] L Yang, X Chen, L Wang, Z Hu, N Xin, M Hippler, W Zhu, Y Hu^*, J Li, Y. C. Wang, L Zhang, D Wu^*, J Chu. Targeted single-cell therapeutics with magnetic tubular micromotor by one-step exposure of structured femtosecond optical vortices. Advanced Functional Materials. 2019, 29(45): 1905745.

[2] P. Chen^#, Y. Ma^#, Z. Zheng^#, C. Wu, Y. C. Wang^*, G. L. Liang^*. Facile syntheses of conjugated polymers for photothermal tumour therapy. Nature Communications. 2019, 10(1): 1192.

[3] Y. Ma^#, Y. Zhang^#, X. Li^#, Y. Zhao, M. Li, W. Jiang, X. Tang, J. Dou, L. Lu, F. Wang^*, Y. C. Wang^*. Near-infrared II phototherapy induces deep tissue immunogenic cell death and potentiates cancer immunotherapy. ACS Nano. 2019, 13(10): 11967-11980.

[4] Y. Ma^#, Y. Zhao^#, N. K. Bejjanki^#, X. Tang, W. Jiang, J. Dou, M. I. Khan, Q. Wang, J. Xia, H. Liu, Y. You, G. Zhang, Y. C. Wang^*, J. Wang^*. Nanoclustered cascaded enzymes for targeted tumor starvation and deoxygenation-activated chemotherapy without systemic toxicity. ACS Nano. 2019, 13(8): 8890-8902.

[5] Y. Zhang^#, Y. Zhao^#, J. Shen^#, X. Sun, Y. Liu, L. Hang, H. Liu, Y. C. Wang^*, J. Wang^*. Nanoenabled modulation of acidic tumor microenvironment reverses anergy of infiltrating T cells and potentiates anti-PD-1 therapy. Nano Letters. 2019, 19(5): 2774-2783.

[6] W. Jiang^#, Z. Zhang^#, Q. Wang^#, J. Dou, Y. Zhao, Y. Ma, H. Liu, H. X. Xu^*, Y. C. Wang^*. Tumor reoxygenation and blood perfusion enhanced photodynamic therapy using ultrathin graphdiyne oxide nanosheets. Nano Letters. 2019, 19(6): 4060-4067.

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[8] Y. Liu^#, N. K. Bejjanki^#, W. Jiang, Y. Zhao, L. Wang, X. Sun, X. Tang, H. Liu^*, Y. C. Wang^*. Controlled syntheses of well-defined poly(thionophosphoester)s that undergo peroxide-triggered degradation. Macromolecules. 2019, 52(11): 4306-4316.

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[1] L. Huang, B. Chen, X. Zhang, C. Trindle, F. Liao, Y. C. Wang, H. Miao, Y. Luo, G. Zhang^*. Proton-activated "off-on" room-temperature phosphorescence from purely organic thioethers. Angewandte Chemie International Edition. 2018, 57(49): 16046-16050.

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[3] W. Jiang, J. Wang, J. Yang, Z. He, G. Zhang, F. Huang, X. Zhou, L.F. Yan^*, X. Z. Yang^*, Y. C. Wang^*, J. Wang. Acidity-triggered TAT-presenting nanocarriers augment tumor retention and nuclear translocation of drugs. Nano Research. 2018, 11(10): 5716-5734.

[4] X. Wang^#, Y. Ma^#, X. Sheng, Y. C. Wang^*, H. Xu^*. Ultrathin polypyrrole nanosheets via space-confined synthesis for efficient photothermal therapy in the second near-infrared window. Nano Letters. 2018, 18(4): 2217-2225.

[5] W. Jiang^#, Q. Li^#, Z. Zhu^#, Q. Wang, J. Dou, Y. Zhao, W. Lv, F. Zhong, Y. Yao, G. Zhang, H. Liu^*, Y. C. Wang^*, J. Wang. Cancer chemoradiotherapy duo: nano-enabled targeting of DNA lesion formation and DNA damage response. ACS Applied Materials & Interfaces. 2018, 10(42): 35734-35744.

[6] Z. Ruan^#, Y. Zhao^#, P. Yuan, L. Liu, Y. C. Wang^*, L. Yan^*. PEG conjugated BODIPY-Br2 as macrophotosensitizer for efficient imaging-guided photodynamic therapy. Journal of Materials Chemistry B. 2018, 6(5): 753-762.

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[8] Z. Zhao^#, J Long^#, Y. Zhao, J. Yang, W Jiang, Q. Liu, K Yan, L Li, Y. C. Wang^*, Z. X. Lian^*. Adaptive immune cells are necessary for the enhanced therapeutic effect of sorafenib-loaded nanoparticles. Biomaterials Science. 2018, 6(4): 893-900.

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[1] J. Chen, J. Ding^*, Y. C. Wang, J. Cheng^*, S. Ji, X. Zhuang, X. Chen^*. Sequentially responsive shell-stacked nanoparticles for deep penetration into solid tumors. Advanced Materials. 2017, 29(32):1701170.

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[4] J. Chen^#, S. Li^#, Y. Zhang, W. Wang, X. Zhang, Y. Zhao, Y. C. Wang^*, H. Bi^*. A reloadable self-healing hydrogel enabling diffusive transport of C-dots across gel-gel interface for scavenging reactive oxygen species. Advanced Healthcare Materials. 2017, 6(21):1700746.

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[1] Y. Jiang^#, J. L. Carvalho-de-Souza^#, R. C. S. Wong^#, Z. Luo, D. Isheim, X. Zuo, A. W. Nicholls, I. W. Jung, J. Yue, D. J. Liu, Y. C. Wang, V. De Andrade, X. Xiao, L. Navrazhnykh, D. E. Weiss, X. Wu, D. N. Seidman, F. Bezanilla^*, B. Tian^*. Heterogeneous silicon mesostructures for lipid-supported bioelectric interfaces. Nature Materials. 2016, 15(9):1023-1030.

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[7] M. Zhang^*, S. Li, X. Yan, Z. Zhou, M. L. Saha, Y. C. Wang^*, P. J. Stang^*. Fluorescent metallacycle-cored polymers via covalent linkage and their use as contrast agents for cell imaging. Proceedings of the National Academy of Sciences of the United States of America. 2016, 113(40):11100-11105.

[8] N. Zhou, L. Tian, Y. C. Wang, D. Li, P. Li, X. Zhang, H. Q. Yu^*. Extracellular biosynthesis of copper sulfide nanoparticles by Shewanella oneidensis MR-1 as a photothermal agent. Enzyme and Microbial Technology. 2016, 95:230-235.

[1] Z. Luo^#, Y. Jiang^#, B. D. Myers, D. Isheim, J. Wu, J. F. Zimmerman, Z. Wang, Q. Li, Y. C. Wang, X. Chen, V. P. Dravid, D. N. Seidman, B. Tian^*. Atomic gold-enabled three-dimensional lithography for silicon mesostructures. Science. 2015, 348(6242):1451–1455.

[2] J. F. Zimmerman^#, G. F. Murray,Y. C. Wang, J. M. Jumper, J. R. Austin, B. Tian^*. Free-standing kinked silicon nanowires for probing inter- and intracellular force dynamics. Nano Letters. 2015, 15(8):5492–5498.

[1] Y. C. Wang^#, M. S. Shim^#, N. S. Levinson, H.-W. Sung, Y. Xia^*. Stimuli-responsive materials for controlled release of theranostic agents. Advanced Functional Materials. 2014, 24(27):4206–4220.

[2] K. C. L. Black^#, Y. C. Wang^#, H. P. Luehmann, X. Cai, W. Xing, B. Pang, Y. Zhao, C. S. Cutler, L. V. Wang, Y. Liu^*, Y. Xia^*. Radioactive ¹⁹⁸Au-doped nanostructures with different shapes for in vivo analyses of their biodistribution, tumor uptake, and intratumoral distribution. ACS Nano. 2014, 8(5):4385–4394.

[3] T. M. Sun^#, Y. C. Wang^#, F. Wang, J. Z. Du, C. Q. Mao, C. Y. Sun, R. Z. Tang, Y. Liu, J. Zhu, Y. H. Zhu, X. Z. Yang, J. Wang^*. Cancer stem cell therapy using doxorubicin conjugated to gold nanoparticles via hydrazone bonds. Biomaterials. 2014, 35(2):836–845.

[4] T. Sun^#, Y. Wang, Y. C. Wang, J. Xu, X. Zhao, S. Vangveravong, R. H. Mach, Y. Xia^*. Using SV119-gold nanocage conjugates to eradicate cancer stem cells through a combination of photothermal and chemo therapies. Advanced Healthcare Materials. 2014, 3(8):1283–1291.

[1] Y. C. Wang^#, K. C. L. Black^#, H. Luehmann, W. Li, Y. Zhang, X. Cai, D. Wan, S. Liu, M. Li, P. Kim, Z. Li, L. V. Wang, Y. Liu^*, Y. Xia^*. A comparison study of gold nanohexapods, nanorods, and nanocages for photothermal cancer treatment. ACS Nano. 2013, 7(3):2068–2077.

[2] K. J. Chen^#, H. F. Liang, H. L. Chen, Y. C. Wang, P. Y. Cheng, H. L. Liu, Y. Xia^*, H. W. Sung^*. A thermoresponsive bubble-generating liposomal system for triggering localized extracellular drug delivery. ACS Nano. 2013, 7(1):438–446.

[3] Y. S. Zhang^#, Y. Wang, L. Wang, Y. C. Wang, X. Cai, C. Zhang, L. V. Wang, Y. Xia^*. Labeling human mesenchymal stem cells with gold nanocages for in vitro and in vivo tracking by two-photon microscopy and photoacoustic microscopy. Theranostics. 2013, 3(8):532–543.

[4] H. X. Wang^#, M.-H. Xiong, Y. C. Wang, J. Zhu, J. Wang^*. N-acetylgalactosamine functionalized mixed micellar nanoparticles for targeted delivery of siRNA to liver. Journal of Controlled Release. 2013, 166(2):106–114.

[5] D. Wan^#, X. Xia, Y. C. Wang, Y. Xia^*. Robust synthesis of gold cubic nanoframes through a combination of galvanic replacement, gold deposition, and silver dealloying. Small. 2013, 9(18):3111–3117.

[6] W. Q. Li^#, F. Wang, Z. M. Liu, Y. C. Wang, J. Wang^*, F. Sun^*. Gold nanoparticles elevate plasma testosterone levels in male mice without affecting fertility. Small. 2013, 9(9–10):1708–1714.

[7] Y. C. Wang^#, Y. Liu^#*, H. Luehmann, X. Xia, D. Wan, C. Cutler, Y. Xia^*. Radioluminescent gold nanocages with controlled radioactivity for real-time in vivo imaging. Nano Letters. 2013, 13(2):581–585.

[8] W. Li^#, C. Sun, F. Wang, Y. C. Wang, Y. Zhai, M. Liang, W. Liu, Z. Liu, J. Wang^*, F. Sun^*. Achieving a new controllable male contraception by the photothermal effect of gold nanorods. Nano Letters. 2013, 13(6):2477–2484.

[9] J. Wu^#, T. M. Sun^#, X. Z. Yang^*, J. Zhu, X. J. Du, Y. D. Yao, M. H. Xiong, H. X. Wang, Y. C. Wang, J. Wang^*. Enhanced drug delivery to hepatocellular carcinoma with a galactosylated core-shell polyphosphoester nanogel. Biomaterials Science. 2013, 1(11):1143–1150.

[1] Y. C. Wang, Y. Liu^*, H. Luehmann, X. Xia, P. Brown, C. Jarreau, M. Welch, Y. Xia^*. Evaluating the pharmacokinetics and in vivo cancer targeting capability of Au nanocages by positron emission tomography imaging. ACS Nano. 2012, 6(7):5880–5888.

[2] X. Xia, M. Yang, Y. C. Wang, Y. Zheng, Q. Li, J. Cheng^*, Y. Xia^*. Quantifying the coverage density of poly (ethylene glycol) chains on the surface of gold nanostructures. ACS Nano. 2012, 6(1):512–522.

[3] X. Yang, S. Dou, Y. C. Wang, H. Long, M. Xiong, C. Mao, Y. Yao, J. Wang^*. Single-step assembly of cationic lipid–polymer hybrid nanoparticles for systemic delivery of siRNA. ACS Nano. 2012, 6(6):4955–4965.

[4] M. Xiong, Y. Bao, X. Yang, Y. C. Wang, B. Sun^*, J. Wang^*. Lipase-sensitive polymeric triple-layered nanogel for “on-demand” drug delivery. Journal of the American Chemical Society. 2012, 134(9):4355–4362.

[5] Y. C. Wang, Y. Wang, F. Zhou, P. Kim, Y. Xia^*. Protein-protected Au clusters as a new class of nanoscale biosensor for label-free fluorescence detection of proteases. Small. 2012, 8(24):3769–3773.

[6] Y. C. Wang, J. Xu, X. Xia, M. Yang, S. Vangveravong, J. Chen, R. H. Mach, Y. Xia^*. SV119-gold nanocage conjugates: a new platform for targeting cancer cells via sigma-2 receptors. Nanoscale. 2012, 4(2):421–424.

[7] S. Xie, M. Jin, J. Tao, Y. C. Wang, Z. Xie, Y. Zhu, Y. Xia^*. Synthesis and characterization of Pd@MₓCu₁₋ₓ (M = Au, Pd, and Pt) nanocages with porous walls and a yolk–shell structure through galvanic replacement reactions. Chemistry – A European Journal. 2012, 18(47):14974–14980.

[1] Y. C. Wang, P. Brown, Y. Xia^*. Swarming towards the target. Nature Materials. 2011, 10(7):482–483.

[2] F. Wang^#, Y. C. Wang^#, S. Dou, M. Xiong, T. Sun, J. Wang^*. Doxorubicin-tethered responsive gold nanoparticles facilitate intracellular drug delivery for overcoming multidrug resistance in cancer cells. ACS Nano. 2011, 5(5):3679–3692.

[3] P. O. Rujitanaroj, Y. C. Wang, J. Wang, S. Y. Chew^*. Nanofiber-mediated controlled release of siRNA complexes for long term gene-silencing applications. Biomaterials. 2011, 32(25):5915–5923.

[4] Y. C. Wang^#, F. Wang^#, T. Sun, J. Wang^*. Redox-responsive nanoparticles from the single disulfide bond-bridged block copolymer as drug carriers for overcoming multidrug resistance in cancer cells. Bioconjugate Chemistry. 2011, 22(10):1939–1945.

[5] Y. C. Wang, Y. Yuan, F. Wang, J. Wang^*. Syntheses and characterization of block copolymers of poly (aliphatic ester) with clickable polyphosphoester. Journal of Polymer Science Part A: Polymer Chemistry. 2011, 49(2):487–494.

[1] Y. Yuan, Q. Du, Y. C. Wang, J. Wang^*. One-pot syntheses of amphiphilic centipede-like brush copolymers via combination of ring-opening polymerization and “click” chemistry. Macromolecules. 2010, 43(4):1739–1746.

[2] Y. C. Wang, Y. Li, T. Sun, M. Xiong, J. Wu, Y. Yang, J. Wang^*. Core–shell–corona micelle stabilized by reversible cross-linkage for intracellular drug delivery. Macromolecular Rapid Communications. 2010, 31(13):1201–1206.

[3] P. Zhang, L. Hu, Y. C. Wang, J. Wang, L. Feng, Y. P. Li^*. Poly (ε-caprolactone)-block-poly (ethyl ethylene phosphate) micelles for brain-targeting drug delivery: in vitro and in vivo evaluation. Pharmaceutical Research. 2010, 27(12):2657–2669.

[4] Y. C. Wang, J. Wu, Y. Li, J. Du, Y. Yuan, J. Wang^*. Engineering nanoscopic hydrogels via photo-crosslinking salt-induced polymer assembly for targeted drug delivery. Chemical Communications. 2010, 46(20):3520–3522.

[1] L. Tang, Y. Li, J. Du, Y. C. Wang^*, J. Wang^*. Shell-detachable micelles based on disulfide-linked block copolymer as potential carrier for intracellular drug delivery. Bioconjugate Chemistry. 2009, 20(6):1095-1099.

[2] X. Yang, T. Sun, S. Dou, J. Wu, Y. C. Wang, J. Wang^*. Block copolymer of polyphosphoester and poly (L-lactic acid) modified surface for enhancing osteoblast adhesion, proliferation, and function. Biomacromolecules. 2009, 10(8):2213-2220.

[3] Y. C. Wang, Y. Yuan, J. Du, X. Yang, J. Wang^*. Recent progress in polyphosphoesters: from controlled synthesis to biomedical applications. Macromolecular Bioscience. 2009, 9(12):1154-1164.

[4] Y. C. Wang, Y. Li, X. Yang, Y. Yuan, L. Yan, J. Wang^*. Tunable thermosensitivity of biodegradable polymer micelles of poly (ε-caprolactone) and polyphosphoester block copolymers. Macromolecules. 2009, 42(8):3026-3032.

[5] Y. C. Wang, L. Tang, J. Wang^*. Thermoresponsive block copolymers of poly (ethylene glycol) and polyphosphoester: thermo-induced self-assembly, biocompatibility and hydrolytic degradation. Biomacromolecules. 2009, 10(1):66-73.

[6] Y. C. Wang, H. Xia, X. Z. Yang, J. Wang^*. Synthesis and thermoresponsive behaviors of biodegradable pluronic analogs. Journal of Polymer Science Part A: Polymer Chemistry. 2009, 47(8):6168-6179.

[7] F. Wang, Y. C. Wang, L. Yan, J. Wang^*. Biodegradable vesicular nanoparticles based on block copolymer of poly (ε-caprolactone) and poly (ethyl ethylene phosphate) for drug delivery. Polymer. 2009, 50(21):5048-5054.

[8] J. Wu, X. Liu, Y. C. Wang, J. Wang^*. Template-free synthesis of biodegradable nanogels with tunable sizes as potential carriers for drug delivery. Journal of Materials Chemistry. 2009, 19(42):7856-7863.

[9] Y.Yuan, X. Liu, Y. C. Wang, J. Wang^*. Gold nanoparticles stabilized by thermosensitive diblock copolymers of poly (ethylene glycol) and polyphosphoester. Langmuir. 2009, 25(17):10298-10304.

[10] M. Xiong, J. Wu, Y. C. Wang, L. Li, X. Liu, G. Zhang, L. Yan, J. Wang^*. Synthesis of PEG-armed and polyphosphoester core-cross-linked nanogel by one-step ring-opening polymerization. Macromolecules. 2009, 42(4):893-896.

[1] J. Cheng, J. Ding, Y. C. Wang, J. Wang^*. Synthesis and characterization of star-shaped block copolymer of poly (ε-caprolactone) and poly (ethyl ethylene phosphate) as drug carrier. Polymer. 2008, 49(12):4784-4790.

[2] Y. C. Wang, L. Tang, T. Sun, C. Li, M. Xiong, J. Wang^*. Self-assembled micelles of biodegradable triblock copolymers based on poly (ethyl ethylene phosphate) and poly (ε-caprolactone) as drug carriers. Biomacromolecules. 2008, 9(1):388-395.

[3] Y. C. Wang, X. Liu, T. Sun, M. Xiong, J. Wang^*. Functionalized micelles from polyphosphoester and poly (ε-caprolactone) block copolymer for receptor-mediated drug delivery. Journal of Controlled Release. 2008, 128(1):32-40.

[4] Y. Yuan, Y. C. Wang, J. Du, J. Wang^*. Synthesis of amphiphilic ABC 3-miktoarm star terpolymer by combination of ring opening polymerization and “click” chemistry. Macromolecules. 2008, 41(22):8620-8625.

[5] X. Yang, Y. C. Wang, L. Tang, H. Xia, J. Wang^*. Synthesis and characterization of amphiphilic block copolymer of polyphosphoester and poly (l-lactic acid). Journal of Polymer Science Part A: Polymer Chemistry. 2008, 46(8):6425-6434.

[1] Y. C. Wang, S. Shen, Q. Wu, D. Chen, G. Steinhoff, N. Ma, J. Wang^*. Block copolymerization of ε-caprolactone and 2-methoxyethyl ethylene phosphate initiated by aluminum isopropoxide: synthesis, characterization, and kinetics. Macromolecules. 2006, 39(26):8992-8998.

[2] C. Xiao, Y. C. Wang, J. Du, X. Chen, J. Wang^*. Kinetics and mechanism of 2-ethoxy-2-oxo-1,3,2-dioxaphospholane polymerization initiated by stannous octoate. Macromolecules. 2006, 39(20):6825-6831.

[3] J. Du, D. Chen, Y. C. Wang, C. Xiao, Y. Lu, G. Zhang, J. Wang^*. Synthesis and micellization of amphiphilic brush-coil block copolymer based on poly (ε-caprolactone) and PEGylated polyphosphoester. Biomacromolecules. 2006, 7(6):1898-1963.