2025

[1] W. Jiang#, Z. Guo#, Q. Wang#,*, Z. Chen, W. Dong, Q. Liang, Y. Hao, H. Pan, C. Zeng, H. Liu* ,Y. C. Wang*. Enhanced nanoparticle delivery across vascular basement membranes of tumours using nitric oxide. Nature Biomedical Engineering. 2025, doi:10.1038/s41551-025-01385-w.

 

[2] Y. Liu#, Q. Liu#, B. Zhang#, S. Chen, Y. Shen, Z. Li, J. Zhang, Y. Yang, M. Li*Y. C. Wang*. Generation of tolerogenic antigen-presenting cells in vivo via the delivery of mRNA encoding PD-L1 within lipid nanoparticles. Nature Biomedical Engineering. 2025, doi:10.1038/s41551-025-01373-0.

 

[3] Z. Shen#, W. Jiang#, S. Zheng, S. Luo, Z. Guo, Q. Wang, Y. C. Wang*, J. M. Hu*. Intracellular co-delivery of carbon monoxide and nitric oxide induces mitochondrial apoptosis for cancer therapy. Angewandte Chemie International Edition. 2025, 64, 7, e2024199.

 

[4] T. Ji, P. Ge, S. Zhang, C. Wan, H. Liu, X. Qu, F. Zhu, Q. Gong, W. Xu, C. Wang*, Y. C. Wang*, C. D. Huang*. Remote on-off switching of protein activity by intrinsically disordered region. Nature Structural & Molecular Biology. 2025, doi:10.1038/s41594-025-01585-7.

 

[5] W. X. Deng#, Y. Wang#, J. Wang, Y. Su, M. Li, K. Qu, Y. C. Wang*, M. Li*. Leveraging vitamin C to augment nanoenabled photothermal immunotherapy. ACS Nano. 2025, 19, 13, 12982-12995.


2024

[1] Q. Wang#, Q. R Liang#, J. X. Dou, H. Zhou, C. C. Zeng, H. M. Pan, Y. Q. Shen, Q. Li, Y. Liu, D. T. Leong*, W. Jiang*, Y. C. Wang*. Breaking through the basement membrane barrier to improve nanotherapeutic delivery to tumors. Nature Nanotechnology. 2024, 19,9, 95-105.

 

[2] M. Luo#, Q. Wang#, G. Zhao#, W. Jiang, C. C. Zeng, Q. A. Zhang, R. Y. Yang, W. Dong, Y. X. Zhao, G. Z. Zhang, J. Jiang, Y. C. Wang*, Q. Zhu*. Solid-state atomic hydrogen as a broad-spectrum RONS scavenger for accelerated diabetic wound healing. National Science Review. 2024, 11, 12, nwad269.

 

[3] H. Zhou#, Y. Wu#, M. Li#, Q. R Liang, W. Dong, Q. Li*,Y. C. Wang*. Modular satellite nanoparticles for remedying primary and secondary injury in cerebral ischemia-reperfusion. Advanced Functional Materials. 2024, 34, 30, 2315274.

 

[4] W. Dong#, Z. B. Li#, T. L. Hou#, Y. Q. Shen, Z. X. Guo, Y. T. Su, Z. Q. Chen, H. M. Pan, W. Jiang*, Y. C. Wang*. Multicomponent synthesis of imidazole-based ionizable lipids for highly efficient and spleen-selective messenger RNA delivery. Journal of the American Chemical Society. 2024, 146, 22, 15085-15095.

 

[5] N. M. Wu#, J. C. Zhang#, Y. Q. Shen#, X. H. Zhang#, J. G. Zhou#, Y. Wu, E. T. Li, X. M. Meng, X. Chuai*, S. Chiu*, Y. C. Wang*. A potential bivalent mRNA vaccine candidate protects against both RSV and SARS-CoV-2 infections. Molecular Therapy. 2024, 32, 4, 1033-1047.

 

[6] Z. X. Guo#, C. C. Zeng #, Y. Q. Shen#, L. Hu, H. Y. Zhang, Z. B. Li, W. Dong, Q. Wang, Q. Liu, Y. C. Wang*, W. Jiang*. Helper lipid-enhanced mRNA delivery for treating metabolic dysfunction-associated fatty liver disease. Nano Letters. 2024, 24, 22, 6743-6752.

 

[7] M. Hassan#, Y.T. Su#, S. Iqbal, R. Nawaz, Y.C. Wang*, W. Jiang*. Symmetrically fluorinated D-p-A structured cyanine dye for highly efficient NIR-II imaging-guided cancer phototheranostics. Small. 2024, 20, 43, 2401905.

 

[8] E. T. Li#, Q. Z. Gong#, J. C. Zhang#, X. P. Guo, W. Y. Xie, D. Chen, Y. Q. Shen, D. X. Hong, Z. H. Li, Q. Q. Wang, C. Wang*, Y. C. Wang*, S. Chiu*. An mpox quadrivalent mRNA vaccine protects mice from lethal vaccinia virus challenge. Antiviral Research. 2024, 230, 10, 105974.

 

[9] 李港,侯泰霖,蒋为,王育才*,聚合物载体在mRNA递送领域的研究进展,《药学进展》,2024,48,6,437-449.


2023

[1] A. X. Cheng#, T. Xu#, W. Y. You, T. Wang, D. M. Zhang, H. M. Guo, H. Y. Zhang, X. Pan, Y. C. Wang, L. Liu, K. G. Zhang, J. Shi, X. B. Yao, J. Guo*, Z. Y. Yang*. A mitotic NADPH upsurge promotes chromosome segregation and tumour progression in aneuploid cancer cells. Nature Metabolism. 2023, 5, 7, 1141-1158.

 

[2] M. I. Setyawati#,*, Q. Wang#, N. Ni, J. K. Tee, K. Ariga, P. C. Ke, H. K. Ho, Y. C. Wang*, D. T. Leong*. Engineering tumoral vascular leakiness with gold nanoparticles. Nature Communications. 2023, 14, 1, 4269.

 

[3] M. Li#, H. Zhou#, M. H. Fang, K. Qu, Y. C. Wang*. Cationic lipids-mediated dual-targeting of both dendritic cells and tumor cells for potent cancer immunotherapy. Advanced Functional Materials. 2023, 33, 46, 2306752.

 

[4] K. Chen#, Z. Zhang#, Z. Y. Fang#, J. C. Zhang, Q. Liu, W. Dong, Y. Liu, Y. C. Wang*, J. Wang*. Aged-signal-eliciting nanoparticles stimulated macrophage-mediated programmed removal of inflammatory neutrophils. ACS Nano. 2023, 17, 14, 13903-13916.

 

[5] Y. Liu#, W. Dong #, Y. Ma, J. Dou, W. Jiang, L. Wang, Q. Wang, S. Li, Y. C. Wang*, M. Li*. Nanomedicines with high drug availability and drug sensitivity overcome hypoxia-associated drug resistance. Biomaterials. 2023, 294, 3, 122023.


[6] Y. Wu#, N. M. Wu#, X. Y. Jia#, Y. Wu#, X. H. Zhang, Y. Liu, Y. X. Hou, Y. Q. Shen, E. T. Li, W. Wang*, Y. C. Wang*, S. Chiu. Long-term immune response to Omicron-specific mRNA vaccination in mice, hamsters, and nonhuman primates. MedComm. 2023, 4,12, e460.

 

[7] Y. C. Xu#, C. Yang#, Y. Wu, W. Jiang, Q. Cheng, L. F. Yan, K.G. Chen*, Y. C. Wang*. In situ albumin-hitchhiking NIR-II probes for accurate detection of micrometastases. Nano Letters. 2023, 23, 12, 5731-5737.

 

[8] M. Li#, H. Zhou#, N. Wu, W. Deng, W. Dong, X. Sun, Z. Tian, Y. C. Wang*. Pathogen recognition-driven dendritic cell-specific gene silencing and editing. Nano Letters. 2023, 23, 7, 2733-2742.

 

[9] K. G. Chen#, Z. Zhang#, J. C. Zhang#, Z. Y. Fang, W. Dong, Y. C. Wang*, M. Li*. Antigen-caged-adjuvant nanovaccines elicit potent humoral and cellular immune responses. Nano Today. 2023, 53, 12, 102036.

 

[10] W. Jiang#, Z. Shen#, Z. Guo#, Q. Wang, Q. Li, J. Hu*Y. C. Wang*. Overcoming oxygen heterogeneity of tumor microenvironments to boost cancer immunotherapy by oxygen-switchable ROS/RNS nanogenerators. Nano Today. 2023, 48, 2, 101696.

 

[11] Q. Liu#, L. Wang#, Y. T. Su, W. Dong, H. R. Wang, Y. Liu, H. Liu*, L. X. Liu*, Y. C. Wang*. Ultrahigh enzyme loading metal-organic frameworks for deep tissue pancreatic cancer photoimmunotherapy. Small. 2023, 20, 10, 305131.

 

[12] W. X. Duan, L. F. Hang, Y. C. Ma, Q. Wang, X. F. Tang, W. Jiang, Y. Wu, W. F. Lv, Y. C. Wang*.Compartmentalized nano-MOFs as co-delivery systems for enhanced antitumor therapy. ACS Applied Materials & Interfaces. 2023, 15, 8, 39039-39052.


2022

[1] Y. Wu#, Y. Shen#, N. Wu#, X. Zhang#, S. Chen, C. Yang, J. Zhou, Y. Wu, D. Chen, L. Wang, Y. Wang, J. Xu, K. Liu, C. Wang, H. Zhang*, N. Xia*, S. Chiu*, Y. C. Wang*. Omicron-specific mRNA vaccine elicits potent immune responses in mice, hamsters, and nonhuman primates. Cell Research. 2022, 32, 10, 949-952.


[2] G. Zhang#, Q. Wang#, W. Tao#, W. Jiang, E. Eran, Y. C. Wang*, S. Zhu*. Glucosylated nanoparticles for the oral delivery of antibiotics to the proximal small intestine protect mice from gut dysbiosis. Nature Biomedical Engineering. 2022, 6, 7, 867-881.

 

[3] Q. Zhu#, W. Jiang#, K. Ye, S. Jin, W. Dong, S. Liu, G. Zhang, C. Tian, Y. Luo, Y. C. Wang*, J. Jiang*. Hydrogenated oxide material for self-targeting and automatic-degrading pthotothermal tumor therapy in the NIR-II bio-window. Advanced Functional Materials. 2022, 32, 4, 2110881.

 

[4] W. Jiang#, W. Dong#, M. Li#, Z. Guo, Q. Wang, Y. Liu, Y. Bi, H. Zhou, Y. C. Wang*. Nitric oxide induces immunogenic cell death and potentiates cancer immunotherapy. ACS Nano. 2022, 16, 3, 3881-3894.

 

[5] L. Wang#, J. Dou#, W. Jiang, Q. Wang, Y. Liu, H. Liu*, Y. C. Wang*. Enhanced intracellular transcytosis of nanoparticles by degrading extracellular matrix for deep tissue radiotherapy of pancreatic adenocarcinoma. Nano Letters. 2022, 22, 17, 6877-6887.

 

[6] Y. Zhu#, X. Tang#, Q. Liu#, Y. Xia, X. Zhai, H. Zhang, D. Duan, H. Wang, W. Zhan, L. Wu, N. Zheng, W. Lv*, Y. C. Wang*, M. Zhou*. Metallic carbonitride MXene based photonic hyperthermia for tumor therapy. Small. 2022, 18, 22, 2200646.


2021

[1] M. J. Cao#, R. Cai#, L. N. Zhao#, M. Y. Guo#, L. M. Wang, Y. C. Wang, L. L. Zhang, X. F. Wang, H. D. Yao, C. Y. Xie, Y. L. Cong, Y. Guan, X. Y. Tao, Y. L. Wan, S. X. Xu, Y. Liu, Y. L. Zhao, C. Y. Chen*. Molybdenum derived from nanomaterials incorporates into molybdenum enzymes and affects their activities in vivo. Nature Nanotechnology. 2021, 16, 6, 708-716.

 

[2] Y. H. Bi#, W. X. Duan#, J. Chen#, T. You*, S. Y. Li, W. Jiang, M. Li, G. Wang, X. Y. Pan, J. Wu, D. Liu, J. Li*, Y. C. Wang*. Neutrophil decoys with anti-inflammatory and anti-oxidative properties reduce secondary spinal cord injury and improve neurological functional recovery. Advanced Functional Materials. 2021, 31, 34, 2102912.

 

[3] W. Jiang#, L. Wang#, Q. Wang, H. Zhou, Y. C. Ma, W. Dong, H. X. Xu*, Y. C. Wang*. Reversing immunosuppression in hypoxic and immune cold tumors with ultrathin oxygen self-supplementing polymer nanosheets under near infrared light irradiation. Advanced Functional Materials. 2021, 31, 3, 2100354.

 

[4] Y. Wu#, W. Jiang#, S. H. Huo#, S. Y. Li, Y.C. Xu, S. G. Ding, J. Zhou, H. Liu*, W. F. Lv*, Y. C. Wang*. Nano-metal-organic-frameworks for treating H2O2-secreting bacteria alleviate pulmonary injury and prevent systemic sepsis. Biomaterials. 2021, 279, 12, 121237.

 

[5] M. Li#, D. Xie#, X. F. Tang#, C. Yang, Y. Q. Shen, H. Zhou, W. X. Deng, J. W. Liu, S. B. Cai, L. Bai*, Y. C. Wang*. Phototherapy facilitates tumor recruitment and activation of natural killer T cells for potent cancer immunotherapy. Nano Letters. 2021, 21, 14, 6304-6313.

 

[6] W. Jiang#, H. Zhou#, Q. Wang#, Z. Chen, W. Dong, Z. Guo, Y. Li, W. Zhao, M. Zhan*, Y. C. Wang*, L. Lu*. High drug loading and pH-responsive nanomedicines driven by dynamic boronate covalent chemistry for potent cancer immunotherapy. Nano Research. 2021, 14, 11,3913-3920.


2020

[1] S. Li#, M. Li#, S. Huo, Q. Wang, J. Chen, S. Ding, Z. Zeng, W. Zhou, Y. C. Wang*, J. Wang*. Voluntary opsonization-enabled precision nanomedicines for inflammation treatment. Advanced Materials. 2020, 33, 3, 2006160.


[2] M. Li#, S. Li#, H. Zhou, X Tang, Y. Wu, W. Jiang, Z. Tian, X. Zhou, X. Yang, Y. C. Wang*. Chemotaxis-driven delivery of nano-pathogenoids for complete eradication of tumors postphototherapy. Nature Communications. 2020, 11, 1, 1126.

 

[3] L. Wang#, W. Jiang#, L. Xiao#, H. J. Li, Z. Q. Chen, Y. Liu, J. X. Dou, S. Y. Li, Q. Wang, W. Han, Y. C. Wang*, H. Liu*. Self-reporting and splitting nanopomegranates potentiate deep tissue cancer radiotherapy via elevated diffusion. ACS Nano. 2020, 14, 7, 8459-8472.

 

[4] Q. Li#, L. Hang#, W. Jiang#, J. Dou, L. Xiao, X. Tang, Y. Yao*, Y. C. Wang*. Pre- and post-irradiation mild hyperthermia enabled by NIR-II for sensitizing radiotherapy. Biomaterials. 2020, 257, 10, 120235.

 

[5] M. Li, H. Zhou, C. Yang, Y. Wu, X. Zhou, H. Liu*, Y. C. Wang*. Bacterial outer membrane vesicles as a platform for biomedical applications: an update. Journal of Controlled Release. 2020, 323, 7, 253-268.

 

[6] S. Li, Q. Wang, Y. Shen, M. Hassan, J. Shen, W. Jiang, Y. Su, J. Chen, L. Bai, W. C. Zhou, Y. C. Wang*. Pseudoneutrophil cytokine sponges disrupt myeloid expansion and tumor trafficking to improve cancer immunotherapy. Nano Letters. 2020, 20, 1, 242-251.

 

[7] M. Li#, H. Zhou#, W Jiang#, C. Yang, H. Miao, Y. C. Wang*. Nanovaccines integrating endogenous antigens and pathogenic adjuvants elicit potent antitumor immunity. Nano Today. 2020, 35, 12, 101007.

 

[8] L. Wang#, S. Li#, W. Jiang, H. Liu, J. Dou, X. Li*, and Y. C. Wang*. Polyphosphoestered nanomedicines with tunable surface hydrophilicity for cancer drug delivery. ACS Applied Materials & Interfaces. 2020, 12, 29, 32312-32320.


2019

[1] P. Chen#, Y. Ma#, Z. Zheng#, C. Wu, Y. C. Wang*, G. L. Liang*. Facile syntheses of conjugated polymers for photothermal tumour therapy. Nature Communications. 2019, 10, 1, 1192.

 

[2] L Yang, X Chen, L Wang, Z Hu, N Xin, M Hippler, W Zhu, Y Hu, J Li, Y. C. Wang, L Zhang, D Wu, J Chu. Targeted single-cell therapeutics with magnetic tubular micromotor by one-step exposure of structured femtosecond optical vortices. Advanced Functional Materials. 2019, 1905745.

 

[3] Y. Ma#, Y. Zhang#, X. Li#, Y. Zhao, M. Li, W. Jiang, X. Tang, J. Dou, L. Lu, F. Wang*, Y. C. Wang*. Near-infrared II phototherapy induces deep tissue immunogenic cell death and potentiates cancer immunotherapy. ACS Nano. 2019, 13, 10, 11967-11980.

 

[4] Y. Ma#, Y. Zhao#, N. K. Bejjanki#, X. Tang, W. Jiang, J. Dou, M. I. Khan, Q. Wang, J. Xia, H. Liu, Y. You, G. Zhang, Y. C. Wang*, J. Wang*. Nanoclustered cascaded enzymes for targeted tumor starvation and deoxygenation-activated chemotherapy without systemic toxicity. ACS Nano. 2019, 13, 8, 8890-8902.

 

[5] Y. Zhang#, Y. Zhao#, J. Shen#, X. Sun, Y. Liu, L. Hang, H. Liu, Y. C. Wang*, J. Wang*. Nanoenabled modulation of acidic tumor microenvironment reverses anergy of infiltrating T Cells and potentiates anti-PD-1 therapy. Nano Letters. 2019, 19, 5, 2774-2783.

 

[6] W. Jiang#, Z. Zhang#, Q. Wang#, J. Dou, Y. Zhao, Y. Ma, H. Liu, H. X. Xu*, Y. C. Wang*. Tumor reoxygenation and blood perfusion enhanced photodynamic therapy using ultrathin graphdiyne oxide nanosheets. Nano Letters. 2019, 19, 6, 4060-4067.

 

[7] Y. Liu#, N. K. Bejjanki#, W. Jiang, Y. Zhao, L. Wang, X. Sun, X. Tang, H. Liu*, Y. C. Wang*. Controlled syntheses of well-defined poly(thionophosphoester)s that undergo peroxide-triggered degradation. Macromolecules. 2019, 52, 11, 4306-4316.

 

[8] H. Wang, Y. Hou, Y. Hu, J. Dou, Y. Shen, Y. C. Wang*, H. Lu*. Enzyme-activatable interferon-poly(α-amino acid) conjugates for tumor microenvironment potentiation. Biomacromolecules. 2019, 20, 8, 3000-3008.

 

[9] W. Huang, X. Zhang, B. Chen, H. Miao, C. O. Trindle, Y. C. Wang, Y. Luo, G. Zhang*. Boosting the triplet activity of heavy-atom-free difluoroboron dibenzoylmethane via sp3 oxygen-bridged electron donors. Chemical Communications. 2019, 55, 1, 67-70.

 

[10] H. Huang, T. Wu, H. Shi, Y. Wu, H. Yang, K. Zhong, Y. C. Wang, Y. Liu*. Modular design of nanobody-drug conjugates for targeted-delivery of platinum anticancer drug with MRI contrast agent. Chemical Communications. 2019, 55, 35, 5175-5178.


[11] B. Chen, X. Zhang, Y. C. Wang, H. Miao, G. Zhang*. Aggregation-induced emission with long-lived room-temperature phosphorescence from methylene-linked organic donor-acceptor structures. Chemistry-An Asian Journal. 2019, 14, 6, 751-754.


2018

[1] W. Jiang#, Q. Li#, L. Xiao#, J. Dou, Y. Liu, W. Yu, Y. Ma, X. Li, Y. You, Z. Tong, H. Liu, H. Liang, L. Lu, X. Xu, Y. Yao*, G. Zhang*, Y. C. Wang*, J. Wang. Hierarchical multiplexing nanodroplets for imaging-guided cancer radiotherapy via DNA damage enhancement and concomitant DNA repair prevention. ACS Nano. 2018, 12, 6, 5684-5698.

 

[2] L. Huang, B. Chen, X. Zhang, C. Trindle, F. Liao, Y. C. Wang, H. Miao, Y. Luo, G. Zhang*. Proton-activated "off-on" room-temperature phosphorescence from purely organic thioethers. Angewandte Chemie International Edition. 2018, 57, 49, 16046-16050.

 

[3] X. Wang#, Y. Ma#, X. Sheng, Y. C. Wang*, H. Xu*. Ultrathin polypyrrole nanosheets via space-confined synthesis for efficient photothermal therapy in the second near-infrared window. Nano Letters. 2018, 18, 4, 2217-2225.

 

[4] W. Jiang, J. Wang, J. Yang, Z. He, G. Zhang, F. Huang, X. Zhou, L. F. Yan*, X. Z. Yang*, Y. C. Wang*, J. Wang. Acidity-triggered TAT-presenting nanocarriers augment tumor retention and nuclear translocation of drugs. Nano Research. 2018, 11,10, 5716-5734.

 

[5] W. Jiang#, Q. Li#, Z. Zhu#, Q. Wang, J. Dou, Y. Zhao, W. Lv, F. Zhong, Y. Yao, G. Zhang, H. Liu*, Y. C. Wang*, J. Wang. Cancer chemoradiotherapy duo: nano-enabled targeting of DNA lesion formation and DNA damage response. ACS Applied Materials & Interfaces. 2018, 10, 42, 35734-35744.

 

[6] Z. Ruan#, Y. Zhao#, P. Yuan, L. Liu, Y. C. Wang*, L. Yan*. PEG conjugated BODIPY-Br2 as macrophotosensitizer for efficient imaging-guided photodynamic therapy. Journal of Materials Chemistry B. 2018, 6, 5, 753-762.


[7] X. Du, J. Wang, S Iqbal, H. Li, Z. Cao, Y. C. Wang, J. Du, J Wang*. The effect of surface charge on oral absorption of polymeric nanoparticles. Biomaterials Science. 2018, 6, 3, 642-650.


[8] Z. Zhao#, J Long#, Y. Zhao, J. Yang, W Jiang, Q. Liu, K Yan, L Li, Y. C. Wang*, Z. X. Lian*. Adaptive immune cells are necessary for the enhanced therapeutic effect of sorafenib-loaded nanoparticles. Biomaterials Science. 2018, 6, 4, 893-900.


2017

[1] J. Chen, J. Ding*, Y. C. Wang, J. Cheng*, S. Ji, X. Zhuang, X. Chen*. Sequentially responsive shell-stacked nanoparticles for deep penetration into solid tumors. Advanced Materials. 2017, 29, 32, 1701170.


[2] J. Yi#, Y. C. Wang#,*, Y. Jiang, I. Jung, W. Liu, V. Andrade, R. Xu, R. Parameswaran, I. Peters, R. Divan, X. Xiao, T. Sun, Y. Lee, W. Park*, B. Tian*. 3D calcite heterostructures for dynamic and deformable mineralized matrices. Nature Communications. 2017, 8, 1, 509.


[3] D. Li#, G. Zhang#, W. Xu#, J. Wang, Y. C. Wang*, L. Qiu, J. Ding*, X. Yang*. Investigating the effect of chemical structure of semiconducting polymer nanoparticle on photothermal therapy and photoacoustic imaging. Theranostics. 2017, 7, 16, 4029-4040.


[4] S. Shen#, H. Li#, K. Chen, Y. C. Wang, X. Yang, Z. Lian, J. Du*, J. Wang*. Spatial targeting of tumor-associated macrophages and tumor cells with a pH-sensitive cluster nanocarrier for cancer chemoimmunotherapy. Nano Letters. 2017, 17, 6, 3822-3829.


[5] J. Chen#, S. Li#, Y. Zhang, W. Wang, X. Zhang, Y. Zhao, Y. C. Wang*, H. Bi*. A reloadable self-healing hydrogel enabling diffusive transport of C-dots across Gel-Gel interface for scavenging reactive oxygen species. Advanced Healthcare Materials. 2017, 6, 21, 1700746.


[6] S. Li#, F. Wang#,*, J. Chen, X. Zhang, Y. C. Wang*, J. Liu*. Dipole orientation matters: longer-circulating choline phosphate than phosphocholine liposomes for enhanced tumor targeting. ACS Applied Materials & Interfaces. 2017, 9, 21, 17736-17744.


[7] Y. Xia, J. Shen, H. Alamri, N. Hadjichristidis, J. P. Zhao*, Y. C. Wang*, G. Zhang. Revealing the cytotoxicity of residues of phosphazene catalysts used for the synthesis of poly(ethylene oxide). Biomacromolecules. 2017, 18, 10, 3233-3237.

 

[8] Y. Zhu, C. Sun, S. Shen, M. I. U. Khan, Y. Zhao, Y. Liu, Y. C. Wang*, J. Wang. A micellar cisplatin prodrug simultaneously eliminates both cancer cells and cancer stem cells in lung cancer. Biomaterials Science. 2017, 5, 8, 1612-1621.


[9] C. Wu, H. Chen, X. Wu, X. Cong, L. Wang, Y. C. Wang, Y. Yang, W. Li*, T. M. Sun*. The influence of tumor-induced immune dysfunction on the immune cell distribution of gold nanoparticles in vivo. Biomaterials Science. 2017, 5, 8, 1531-1536.

 

[10] H. Huang, H. Shi, J. Liu, Y. Min, Y. C. Wang, A. Z. Wang, J. Wang and Y. Liu*. Co-delivery of all-trans-retinoic acid enhances the anti-metastasis effect of albumin-bound paclitaxel nanoparticles. Chemical Communications. 2017, 53, 1, 212-215.


[11] Y. Wang, K. Uetani, S. Liu, X. Zhang, Y. C. Wang, P. Lu, T. Wei, Z Fan, Jing Shen, H. Yu*, S. Li, Q. Zhang, Q. Li, J. Fan, N. Yang, Q. Wang, Y. Liu, J. Cao, J. Li, W. Chen*. Multifunctional bionanocomposite foams with a chitosan matrix reinforced by nanofibrillated cellulose. ChemNanoMat. 2017, 3, 2, 98-108.


2016

[1] Y. Jiang#, J. C. Souza#, R. Wong#, Z. Luo, D. Isheim, X. Zuo, A. Nicholls, I. Jung, J. Yue, D. Liu, Y. C. Wang, V. De. Andrade, X. Xiao, L. Navrazhnykh, D. Weiss, X. Wu, D. Seidman, F. Bezanilla*, B. Tian*. Heterogeneous silicon mesostructures for lipid-supported bioelectric interfaces. Nature Materials. 2016, 15, 9, 1023-1030.

 

[2] J. Wang, Y. Liu, Y. Ma, C. Sun, W. Tao, Y. C. Wang, X. Yang*, J. Wang. NIR-activated super-sensitive drug release using nanoparticles with a flow core. Advanced Functional Materials. 2016, 26, 9, 7516-7516.

 

[3] Z. Cao, Z. Chen, C. Sun, H. Li, H. Wang, Q. Cheng, Z. Zuo, J. Wang, Y. Liu, Y. C. Wang*, J. Wang*. Overcoming tumor resistance to cisplatin by cationic lipid-assisted prodrug nanoparticles. Biomaterials. 2016, 94, 7, 9-19.

 

[4] Z. Zuo, K. Chen, X. Yu, G. Zhao, S. Shen, Z. Cao, Y. Luo, Y. C. Wang, J. Wang*. Promoting tumor penetration of nanoparticles for cancer stem cell therapy by TGF-β signaling pathway inhibition. Biomaterials. 2016, 82, 3, 48-59.

 

[5] J. Zimmerman, R. Parameswaran, G. Murray, Y. C. Wang, M. Burke, B. Tian*. Cellular uptake and dynamics of unlabeled free standing silicon nanowires. Science Advances. 2016, 2, 12, e1601039.

 

[6] M. Zhang*, S. Li, X. Yan, Z. Zhou, M. L. Saha, Y. C. Wang*, P. J. Stang*. Fluorescent metallacycle-cored polymers via covalent linkage and their use as contrast agents for cell imaging. Proceedings of the National Academy of Science. 2016, 113, 40, 11100-11105.


[7] H. Wang, Z. Zuo, J. Du, Y. C. Wang*, R. Sun, Z. Cao, X. Ye, J. Wang, K. W. Leong*, J. Wang*. Surface charge critically affects tumor penetration and therapeutic efficacy of cancer nanomedicines. Nano Today. 2016, 11, 2, 133-144.

 

[8] N. Zhou, L. Tian, Y. C. Wang, D. Li, P. Li, X. Zhang, H. Q. Yu*. Extracellular biosynthesis of copper sulfide nanoparticles by shewanella oneidensis MR-1 as a photothermal agent. Enzyme and Microbial Technology. 2016, 95, 12, 230-235.


2015

[1] Z. Luo#, Y. Jiang#, B. Myers, D. Isheim, J. Wu, J. Zimmerman, Z. Wang, Q. Li, Y. C. Wang, X. Chen, V. P. Dravid, D. N. Seidman, B. Tian*. Atomic gold-enabled three-dimensional lithography for silicon mesostructures. Science. 2015, 348, 6242, 1451-1455.

 

[2] J. Zimmerman, M. Murray, Y. C. Wang, J. Jumper, J. Austin, B. Tian*. Free-standing kinked silicon nanowires for probing inter-and intracellular force dynamics. Nano Letters. 2015, 15, 8, 5492-5498.


2014

[1] Y. C. Wang#, M. S. Shim#, N. S. Levinson, H-W. Sung, Y. Xia*. Stimuli-responsive materials for controlled release of theranostic agents. Advanced Functional Materials. 2014, 24, 27, 4206-4220.

 

[2] K. C. L. Black#, Y. C. Wang#, H. P. Luehmann, X. Cai, W. X. Xing, B. Pang, Y. F. Zhao, C. S. Cutler, L. V. Wang, Y. Liu*, Y. Xia*. Radioactive 198Au-doped nanostructures with different shapes for in vivo analyses of their biodistribution, tumor uptake, and intratumoral distribution. ACS Nano. 2014, 8, 5, 4385-4394.

 

[3] T. Sun#, Y. C. Wang#, F. Wang, J. Du, C. Mao, C. Sun, R. Tang, Y. Liu, J. Zhu, Y. Zhu, X. Yang, J. Wang*. Cancer stem cell therapy using doxorubicin conjugated to gold nanoparticles via hydrazone bonds. Biomaterials. 2014, 35, 2, 836-845.

 

[4] T. Sun, Y. Wang, Y. C. Wang, Y. Xia*. Using SV119-gold nanocage conjugates to eradicate cancer stem cells through a combination of photothermal and chemo therapies. Advanced Healthcare Materials. 2014, 3, 8, 1283-1291.


2013

[1] Y. C. Wang#, K. C. L. Black#, H. Luehmann, W. Li, Y. Zhang, X. Cai, D. Wan, S. Liu, M. Li, P. Kim, Z. Li, L. V. Wang, Y. Liu*, Y. Xia*. Comparison study of gold nanohexapods, nanorods, and nanocages for photothermal cancer treatment. ACS Nano. 2013, 7, 3, 2068-2077.

 

[2] K. J. Chen, H. Liang, H. Chen, Y. C. Wang, P. Cheng, H. L. Liu, Y. Xia*, H. W. Sung*. A thermoresponsive bubble-generating liposomal system for triggering localized extracellular drug delivery. ACS Nano. 2013, 7, 1, 438-446.

 

[3] Y. Zhang, Y. Wang, L. Wang, Y. C. Wang, X. Cai, C. Zhang, L. V. Wang, Y. Xia*. Labeling human mesenchymal stem cells with Au nanocages for in vitro and in vivo tracking by two-photon microscopy and photoacoustic microscopy. Theranostics. 2013, 3, 8, 532-543.

 

[4] D. Wan, X. Xia, Y. C. Wang, Y. Xia*. Robust synthesis of gold cubic nanoframes through a combination of galvanic replacement, gold deposition, and silver dealloying. Small. 2013, 9, 18, 3111-3117.

 

[5] W. Li, F. Wang, Z. Liu, Y. C. Wang, J. Wang*, F. Sun*. Gold nanoparticles elevate plasma testosterone levels in male mice without affecting fertility. Small. 2013, 9, 9-10, 1708-1714.

 

[6] H. Wang, M. Xiong, Y. C. Wang, J. Zhu. J. Wang*. N-acetylgalactosamine functionalized mixed micellar nanoparticles for targeted delivery of siRNA to liver. Journal of Controlled Release. 2013, 166, 2, 106-114.


[7] Y. C. Wang, Y. Liu*, H. Luehamn, X. Xia, D. Wan, C. Cutler, Y. Xia*. Radioluminescent gold nanocages with controlled radioactivity for real-time in vivo imaging. Nano Letters. 2013, 13, 1, 2581-2585.

 

[8] W. Li, C. Sun, F. Wang, Y. C. Wang, Y. Zhai, M. Liang, W. Liu, Z. Liu, J. Wang*, F. Sun*. Achieving a new controllable male contraception by the photothermal effect of gold nanorods. Nano Letters. 2013, 13, 6, 2477-2484.

 

[9] J. Wu, T. Sun, X. Yang, J. Zhu, X. Du, Y. Yao, M. Xiong, H. Wang, Y. C Wang, J. Wang*. Enhanced drug delivery to hepatocellular carcinoma with a galactosylated core-shell polyphosphoester nanogel. Biomaterial Sciences. 2013, 1, 11, 1143-1150.


2012

[1] Y. C. Wang, Y. Liu*, H. Luehmann, X. Xia, P. Brown, C. Jarreau, M. Welch, Y. Xia*. Evaluating the pharmacokinetics and in vivo cancer targeting capability of au nanocages by positron emission tomography imaging. ACS Nano. 2012, 6, 7, 5880-5888.

 

[2] X. Xia, M. Yang, Y. C. Wang, Y. Zheng, Q. Li, J. Cheng*, Y. Xia*. Quantifying the coverage density of poly(ethylene glycol) chains on the surface of gold nanostructures. ACS Nano. 2012, 6, 1, 512-522.


[3] X. Yang, S. Dou, Y. C. Wang, H. Long, M. Xiong, C. Mao, Y. Yao. J. Wang*. Single-step assembly of cationic lipid-polymer hybrid nanoparticles for systemic delivery of siRNA. ACS Nano. 2012, 6, 6, 4955-4965.


[4] M. Xiong, Y. Bao, X. Yang, Y. C. Wang, B. Sun*, J. Wang*. Lipase-sensitive polymeric triple-layered nanogel for “on-demand” drug delivery. Journal of the American Chemical Society. 2012, 134, 9, 4355-4362.


[5] Y. C. Wang, Y. Wang, F. Zhou, P. Kim, Y. Xia*. Protein-protected Au clusters as a new class of nanoscale biosensor for label-free fluorescence detection of proteases. Small. 2012, 8, 24, 3769-3773.

 

[6] S. Xie, M. Jin, J. Tao, Y. C. Wang, Z. Xie, Y. Zhu, Y. Xia*. Synthesis and characterization of Pd@MxCu1-x (M=Au, Pd, and Pt) nanocages with porous walls and a yolk-shell structure through galvanic replacement reactions. Chemistry of Materials. 2012, 18, 47, 14974-14980.


2011

[1] Y. C. Wang, P. Brown, Y. Xia*. Swarming towards the target. Nature Materials. 2011, 10, 6, 482-483.


[2] F. Wang#Y. C. Wang#, S. Dou, M. Xiong, T. Sun, J. Wang*. Doxorubicin-tethered responsive gold nanoparticles facilitate intracellular drug delivery for overcoming multidrug resistance in cancer cells. ACS Nano. 2011, 5, 5, 3679-3692.


[3] P. Rujitanaroj, Y. C. Wang, J. Wang, and C. S. Yian*. Nanofiber-mediated controlled release of siRNA complexes for long term gene-silencing applications. Biomaterials. 2011, 32, 25, 5915-5923.


[4] Y. C. Wang, J. Xu, X. Xia, M. Yang, S. Vangverarong, J. Chen, R. H. Mach, Y. Xia*. SV119-gold nanocage conjugates: a new platform for targeting cancer cells via sigma-2 receptors. Nanoscale. 2011, 4, 2, 421-424.


[5] Y. C. Wang#, F. Wang#, T. Sun, J. Wang*. Redox-responsive nanoparticles from the single disulfide bond-bridged block copolymer as drug carriers for overcoming multi-drug resistance in cancer cells. Bioconjugate Chemistry. 2011, 22, 10, 1939-1945.


2010

[1] Y. Yuan, Q. Du, Y. C. Wang, J. Wang*. One-pot syntheses of amphiphilic centipede-like brush copolymers via combination of ring-opening polymerization and "click" chemistry. Macromolecules. 2010, 43, 4, 1739-1746.


[2] Y. C. Wang, Y. Li, T. Sun, M. Xiong, J. Wu, Y. Yang, J. Wang*. Core-shell-corona micelle stabilized by reversible cross-linkage for intracellular drug delivery. Macromolecular Rapid Communications. 2010, 31, 13, 1201-1206.


[3] Y. C. Wang, J. Wu, Y. Li, J. Du, Y. Yuan, J. Wang*. Engineering nanoscopic hydrogels via photo-crosslinking salt-induced polymer assembly for targeted drug delivery. Chemical Communications. 2010, 46, 20, 3520-3522.

 

[4] P. Zhang, L. Hu, Y. C. Wang, J. Wang, L. Feng, Y. P. Li*. Poly(ε-caprolactone)-block-poly(ethyl ethylene phosphate) micelles for brain-targeting drug delivery: in vitro and in vivo evaluation. Pharmaceutical Research. 2010, 27, 12, 2657-2669.

 

[5] Y. C. Wang, Y. Yuan, F. Wang, J. Wang*. Syntheses and characterization of block copolymers of poly(aliphatic ester) with clickable polyphosphoester. Journal of Polymer Science Part A: Polymer Chemistry. 2011, 49, 11, 487-494.


2009

[1] J. Wu, X. Liu, Y. C. Wang, J. Wang*. Template-free synthesis of biodegradable nanogels with tunable sizes as potential carriers for drug delivery. Journal of Materials Chemistry. 2009, 42, 7856-7863.

 

[2] Y. C. Wang, Y. Li, X. Yang, Y. Yuan, L. Yan, J. Wang*. Tunable thermosensitivity of biodegradable polymer micelles of poly(ε-caprolactone) and polyphosphoester block copolymers. Macromolecules. 2009, 42, 8, 3026-3032.

 

[3] M. Xiong, J. Wu, Y. C. Wang, L. Li, X. Liu, G. Zhang, L. Yan, J. Wang*. Synthesis of PEG-armed and polyphosphoester core-cross-linked nanogel by one-step ring-opening polymerization. Macromolecules. 2009, 42, 4, 893-896.

 

[4] Y. C. Wang, L. Tang, J. Wang*. Thermoresponsive block copolymers of poly(ethylene glycol) and polyphosphoester: thermo-induced self-assembly, biocompatibility and hydrolytic degradation. Biomacromolecules. 2009, 10, 1, 66-73.

 

[5] X. Yang, T. Sun, S. Dou, J. Wu, Y. C. Wang, J. Wang*. Block copolymer of polyphosphoester and poly(l-lactic acid) modified surface for enhancing osteoblast adhesion, proliferation, and function. Biomacromolecules. 2009, 10, 8, 2213-2220.

 

[6] L. Tang, Y. C. Wang*, Y. Li, J. Du, J. Wang*. Shell-detachable micelles based on disulfide-linked block copolymer as potential carrier for intracellular drug delivery. Bioconjugate Chemistry. 2009, 20, 6, 1095-1099.


[7] F. Wang, Y. C. Wang, L. Yan, J. Wang*. Biodegradable vesicular nanoparticles based on block copolymer of poly(e-caprolactone) and poly(ethyl ethylene phosphate) for drug delivery. Polymer. 2009, 50, 21, 5048-5054.

 

[8]  Y. C. Wang, Y. Yuan, J. Du, X. Yang, J. Wang*. Recent progress in polyphosphoesters: from controlled synthesis to biomedical applications. Macromolecular Bioscience. 2009, 9, 12, 1154-1164.

 

[9] Y. Yuan, X. Liu, Y. C. Wang, J. Wang*. Gold nanoparticles stabilized by thermosensitive diblock copolymers of poly(ethylene glycol) and polyphosphoester. Langmuir. 2009, 25, 17, 10298-10304.

 

[10] Y. C. Wang, H. Xia, X. Z. Yang, J. Wang*. Synthesis and thermoresponsive behaviors of biodegradable pluronic analogs. Journal of Polymer Science Part A: Polymer Chemistry. 2009, 47, 8, 6168-6179.


2008

[1] Y. C. Wang, X. Liu, T. Sun, M. Xiong, J. Wang*. Functionalized micelles from polyphosphoester and poly(e-caprolactone) block copolymer for receptor-mediated drug delivery. Journal of Controlled Release. 2008, 128, 1, 32-40.


[2] Y. Yuan, Y. C. Wang, J. Du, J. Wang*. Synthesis of amphiphilic ABC 3-miktoarm star terpolymer by combination of ring opening polymerization and “click” chemistry. Macromolecules. 2008, 41, 22, 8620-8625.


[3] Y. C. Wang, L. Tang, T. Sun, C. Li, M. Xiong, J. Wang*. Self-assembled micelles of biodegradable triblock copolymers based on poly(ethyl ethylene phosphate) and poly(e-caprolactone) as drug carriers. Biomacromolecules. 2008, 9, 1, 388-395.


[4] J. Cheng, J. Ding, Y. C. Wang, J. Wang*. Synthesis and characterization of star-shaped block copolymer of poly(e-caprolactone) and poly(ethyl ethylene phosphate) as drug carrier. Polymer. 2008, 49, 12, 4784-4790.

 

[5] X. Yang, Y. C. Wang, L. Tang, H. Xia, J. Wang*. Synthesis and characterization of amphiphilic block copolymer of polyphosphoester and poly(l-lactic acid). Journal of Polymer Science Part A: Polymer Chemistry, 2008, 46, 8, 6425-6434.


2006

[1] Y. C. Wang, S. Shen, Q. Wu, D. Chen, J. Wang*. Gustav. Steinhoff, Nan. Ma. Block copolymerization of ε-caprolactone and 2-methoxyethyl ethylene phosphate initiated by aluminum isopropoxide: synthesis, characterization, and kinetics. Macromolecules. 2006, 39, 26, 8992-8998.

 

[2] C. Xiao, Y. C. Wang, J. Du, X. Chen, J. Wang*. Kinetics and mechanism of 2-ethoxy-2-oxo-1,3,2-dioxaphospholane polymerization initiated by stannous octoate. Macromolecules. 2006, 39, 20, 6825-6831.

 

[3] J. Du, D. Chen, Y. C. Wang, C. Xiao, Y. Lu, J. Wang*, G. Zhang. Synthesis and micellization of amphiphilic brush-coil block copolymer based on poly(ε-caprolactone) and PEGylated polyphosphoester. Biomacromolecules. 2006, 7, 6, 1898-1963.


Yucai Wang

Division of Life Sciences and Medicine

National Key Laboratory of Immune Response and Immunotherapy

University of Science and Technology of China

yucaiwang@ustc.edu.cn

(86) 551-63600402

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